Uncapped Giulio Rubini and Carlos Nieto have been added to Italy's lineup for Saturday's Six Nations match against Wales.

With Gonzalo Garcia out injured, Mirco Bergamasco has moved over to centre and Rubini will play on the wing.

Nieto replaces Martin Castrogiovanni, who will start on the bench.

Australian-born Luke McLean has again beat Luciano Orquera into the starting flyhalf position.

Italy is still without fullback Andrea Masi, who has completed a three-match ban but he now has a neck injury.

Italy has lost its three opening games to England, Ireland and Scotland.

Defending champion Wales lost to France two weeks ago to relinquish its chances of a second straight Grand Slam but is still in contention for the Six Nations title.

Italy: Andrea Marcato, Giulio Rubini, Gonzalo Canale, Mirco Bergamasco, Matteo Pratichetti, Luke McLean, Paul Griffen; Salvatore Perugini, Leonardo Ghiraldini, Carlos Nieto, Santiago Dellape, Marco Bortolami, Alessandro Zanni, Mauro Bergamasco, Sergio Parisse. Res: Francesco Sbaraglini, Martin Castrogiovanni, Carlo Antonio Del Fava, Josh Sole, Pablo Sanavosio, Luciano Orquera, Roberto Quartaroli.

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