NRL clubs have been left counting the cost of a brutal Origin series finale with several players from both NSW and Queensland camps in doubt for this weekend's round of matches.

The Blues won a spiteful game 28-16 to deny Queensland an Origin clean sweep, the match ending in dramatic circumstances with Trent Waterhouse sent off and Ben Creagh and Sam Thaiday sin-binned as hostilities overtook the final result.

And the consequences of the tough contest are set to be felt for some weeks to come.

Manly winger David Williams is nursing a suspected fractured cheekbone after he was kicked in the head by Maroons halfback Johnathan Thurston in an incident which eventually led to an eight-point try being awarded.

Johnathan was slapped with a dangerous conduct charge, but will be free to play for North Queensland this weekend after accepting the early guilty plea.

Waterhouse was also charged for his hit which floored Maroon prop Steve Price with one minute left in the contest, the Panthers backrower facing a one week suspension for a contrary conduct charge.

Price was knocked unconscious during the incident, which was sparked by a flurry of punches between Price and NSW prop Brett White, and he would be in some doubt for the Warriors game against the Roosters on Sunday.

Melbourne duo Cameron Smith (shoulder) and Greg Inglis (corked leg) would also be in some doubt to back up, as would the Cowboys' Willie Tonga who strained his hamstring in the first half.

NSW utility Craig Wing copped a knock to his jaw and will continue to be monitored ahead of Friday night's game against Brisbane at Suncorp Stadium.

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